Package:
VIAL (powder for reconstitution): 1, 10. Dosage:
See prescribing information for full details. Prescribing Restrictions:
Indications:
Neoplastic diseases. See prescribing information for full details. Contra-Indications:
Hypersensitivity or idiosyncratic reaction to drug. Special Precautions:
Patients with significant impairment of renal function or compromised pulmonary function. A severe idiosyncratic reaction consisting of hypotension, mental confusion, fever, chills and wheezing has been reported in 1% of lymphoma patients treated, usually after the first or second dose. Therefore, careful monitoring is essential after these doses. Pregnancy and lactation: If used during pregnancy, or if the patient becomes pregnant while receiving this drug, the patient should be apprised of the potential hazard to the fetus. Women should be advised to avoid becoming pregnant during therapy. It is recommended that nursing be discontinued during therapy. See prescribing information for full details. Side Effects:
Pneumonitis, occasionally progressing to pulmonary fibrosis. Idiosyncratic reactions. Skin toxicity is a relatively late manifestation usually developing in the 2nd and 3rd week of treatment. Fever chills and vomiting are frequent. Anorexia and weight loss. Pain at tumor site, phlebitis and other local reactions were reported infrequently. See prescribing information for full details. Drug Interactions:
See prescribing information for full details
