Package:
VIALS: 1. Dosage:
Initially: 910 mg/m2 1 x daily as 15 minute I.V. infusion starting within 30 minutes prior to chemotherapy. Antihypertension therapy to be interrupted 24 hours prior to chemotherapy. Protection against toxicities associated with radiation therapy: 200 mg/m2 as 3-minute I.V. infusion, starting within 15-30 minutes prior to radiation therapy. See prescribing information for full details. Prescribing Restrictions:
Indications:
Reduction of cumulative renal toxicity associated with repeated administration of cisplatin in advanced ovarian cancer or non-small cell lung cancer, in association with standard fract. radiation therapy to protect against acute and late xerostomia in head and neck cancer. Contra-Indications:
See prescribing information for full details. Special Precautions:
See prescribing information for full details. Side Effects:
See prescribing information for full details. Drug Interactions:
Antihypertensives.