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JEVTANA

Package:
VIAL: 1 + diluent.
Dosage:
The individual dosage is based on calculation of the body surface area (BSA) and is 25 mg/m² administered as a one-hour IV infusion every three weeks in combination with oral prednisone 10 mg administered daily throughout treatment. 
The dose should be reduced to 20 mg/m² following some adverse reactions. See prescribing information for full details.
The single-use vial requires two dilutions prior to administration. See prescribing information for full details.
Prescribing Restrictions:    


Indications:
In combination with prednisone for the treatment of patients with metastatic hormone-refractory prostate cancer (mHRPC) previously treated with a docetaxel-based treatment regimen.
Contra-Indications:
Patients with neutrophil counts of < 1,500/mm³. Patients with a history of severe hypersensitivity reactions to cabazitaxel or to other drugs formulated with polysorbate 80.
Special Precautions:
See prescribing information for full details.
Side Effects:
See prescribing information for full details.
Drug Interactions:
See prescribing information for full details.